The majority of vitamins, supplements and herbal remedies are not evaluated by the Food and Drug Administration (FDA). These products are not intended to diagnose, treat, cure or prevent any disease.1

In effect, because legally they are in a class by themselves, dietary supplements in the US can be marketed without the FDA being satisfied that they are safe. This makes it relatively easy for a manufacturer to market a product without investing the time and money required for its safety.1

Like conventional medicines, dietary supplements may cause side effects, trigger allergic reactions, or interact with prescription and nonprescription medicines or other supplements you might be taking. A side effect or interaction with another medicine or supplement may make other health conditions worse. 2

The way dietary supplements are manufactured may not be standardized. Because of this, how well they work or any side effects they cause may differ among brands or even within different lots of the same brand. The form of supplement that you buy in health food or grocery stores may not be the same as the form used in research.

Other than for vitamins and minerals, the long-term effects of most dietary supplements are not known. 2

  1. https://www.pharmaceutical-journal.com/1-what-is-a-nutraceutical/20002095.article?firstPass=false

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